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Filtered Search Results
MEDCHEMEXPRESS LLC 1H-Indole-3-carboxylic acid, methyl ester | 942-24-5 | 99.9% | C10H9NO2 | 25 G
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Methyl indole-3-carboxylate is a Sorangium metabolite. It exhibits weak activity against Gram-positive Nocardia sp. with a MIC of 33.3 μg/mL. This product is for research use only.
- Shows weak activity against Gram-positive Nocardia sp.
- Does not show significant cytotoxicity against L929, PC-3, and KB3-1 cells with IC50 values > 56.8 μM.
- Available in solid and solution forms.
- Can be dissolved in DMSO for in vitro experiments.
- Protocols for in vivo dissolution are provided using combinations of DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil.
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MEDCHEMEXPRESS LLC Indole-C2-amide-C2-NH2 | 215789-29-0 | 231.29 | 25 MG
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Indole-C2-amide-C2-NH2 is a potent linker used for research purposes only. This product is not for sale to patients.
- Others
- Antibody-drug conjugate/ADC related
- ADC linker
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MEDCHEMEXPRESS LLC (Rac)-Monepantel sulfone-d5 | 2747918-68-7 | 99.8% | 510.42 | 5 MG
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(Rac)-Monepantel sulfone-d5 is a deuterium-labeled form of Monepantel, an organic anthelmintic. It acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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MEDCHEMEXPRESS LLC 3-nitrooxypropanol | 100502-66-7 | MFCD31731012 | 95.0% | C3H7NO4 | 10MG
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Abrucomstat (3-nitrooxypropanol) is a small-molecule inhibitor of methyl coenzyme M reductase that reduces ruminal methanogenesis. It is used in research on enteric methane mitigation and animal nutrition. Reported properties include CAS 100502-66-7, molecular formula C3H7NO4, molecular weight 121.09, and reported purity 95.0%.
- Inhibits methyl coenzyme M reductase and reduces methane production in ruminants.
- Orally active mechanism suited for in vivo rumen studies.
- Supports research on enteric methane mitigation and feed efficiency.
- Small molecular weight with a simple chemical structure for analytical work.
- Supplied with a certificate of analysis indicating reported purity.
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![MEDCHEMEXPRESS LLC Alanine, n-[[5-chloro-2-(3-cyanophenyl)methoxy]-4-(2-methyl-biphenyl-3-yl)methoxy]... | 2377916-66-8 | 98.3% | C33H31ClN2O4 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261267.png-250.jpg)
MEDCHEMEXPRESS LLC Alanine, n-[[5-chloro-2-(3-cyanophenyl)methoxy]-4-(2-methyl-biphenyl-3-yl)methoxy]... | 2377916-66-8 | 98.3% | C33H31ClN2O4 | 10MG
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PD-1/PD-L1-IN-NP19 is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction, reported to block the interaction with an IC50 of 12.5 nM. Supplied as a purified solid for research use, it is intended for in vitro and preclinical studies where modulation of the immune microenvironment is required.
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MEDCHEMEXPRESS LLC Tryptamine guanosine carbamate | 1414808-96-0 | 99.8% | C21H23N7O6 | 10MG
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Tryptamine guanosine carbamate (TpGc) is a small-molecule research reagent that selectively inhibits HINT1 (histidine triad nucleotide-binding protein 1). It is characterized for biochemical and cellular studies, with reported Ki = 34 μM and Kd = 3.65 μM, and is provided as a high-purity solid (molecular formula C21H23N7O6, MW 469.45).
- Selective HINT1 inhibitor (Ki = 34 μM, Kd = 3.65 μM).
- High purity (99.8%).
- Characterized molecular properties (C21H23N7O6; MW 469.45).
- Suitable for biochemical and cellular assays.
- Available in multiple small-scale sizes for research use.
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![EMOLECULES INC 186407-74-9 | 4-Bromo-1H-indazole | Accela ChemBio (ASD) | MFCD05664001 | 197.035 | C7H5BrN2 | 98.000 | Brc1cccc2[nH]ncc12 | 5g | 486446275](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000224874.jpg-250.jpg)
EMOLECULES INC 186407-74-9 | 4-Bromo-1H-indazole | Accela ChemBio (ASD) | MFCD05664001 | 197.035 | C7H5BrN2 | 98.000 | Brc1cccc2[nH]ncc12 | 5g | 486446275
4-Bromo-1H-indazole | Accela ChemBio (ASD) | 186407-74-9 | MFCD05664001 | 197.035 | C7H5BrN2 | 98.000 | Brc1cccc2[nH]ncc12 | 5g | 486446275
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MEDCHEMEXPRESS LLC 9H-fluoren-2-ol-d9 (NSC 31248-d9) | 922510-18-7 | MFCD28899138 | 191.27 | C13HD9O | 1 MG
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9H-Fluoren-2-ol-d9 is the deuterium-labeled form of 9H-fluoren-2-ol (CAS 922510-18-7), provided as a stable-isotope reference standard for analytical and drug-development workflows. The labeled compound (C13HD9O, MW 191.27) is intended for use as a tracer in quantitation, metabolite identification, and pharmacokinetic studies using mass spectrometry and related techniques.
- Deuterium-labeled for use as a stable-isotope tracer.
- Suitable for LC-MS quantitation and metabolite studies.
- Molecular formula C13HD9O and molecular weight 191.27 aid method development.
- Supplied at research-scale quantities appropriate for analytical standards.
- Certificate of analysis and QC reports available on request.
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MEDCHEMEXPRESS LLC 9-ethylcarbazole (N-ethylcarbazole) | 86-28-2 | MFCD00004967 | 100.0% | 195.26 g/mol | C14H13N | 100 G
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9-Ethylcarbazole (N-ethylcarbazole) is an aromatic nitrogen-containing heterocycle used in materials and energy research. It is commonly studied as a liquid organic hydrogen carrier and used as a reagent or building block in organic synthesis, supplied as a high-purity laboratory chemical suitable for analytical and synthetic workflows.
- Used as a liquid organic hydrogen carrier for hydrogen storage research.
- High purity reagent appropriate for analytical and synthetic applications.
- Available in laboratory-scale package sizes including 100 g.
- Stable aromatic heterocycle; chemical formula C14H13N; molar mass 195.26 g/mol.
- Suitable for materials science and organic chemistry research.
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MEDCHEMEXPRESS LLC N-FORMYL DESLORATADI 100 mg
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N-FORMYL DESLORATADI 100MG
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MEDCHEMEXPRESS LLC Tryptamine guanosine carbamate (TpGc) | 1414808-96-0 | MFCD00078028 | 99.8% | 469.45 | 1 MG
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Tryptamine guanosine carbamate (TpGc) is a selective inhibitor of HINT1 (histidine triad nucleotide-binding protein 1). It significantly enhances morphine antinociception and helps prevent the development of tolerance. This compound is for research use only.
- Selective HINT1 inhibitor (Ki=34 μM, Kd=3.65 μM)
- Enhances morphine antinociception
- Prevents development of acute antinociceptive tolerance
- Reduces recruitment of NMDAR activity promoted by morphine
- Attenuates NMDAR function and alleviates mechanical allodynia in chronic constriction injury models
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MEDCHEMEXPRESS LLC Indazole-Cl | 848142-62-1 | 98.19% | 260.68 | 1 MG
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Indazole-Cl (Ind-Cl) is an Estrogen receptor (ER)-β-specific agonist with inflammatory effect. It inhibits cyclooxygenase-2 expression reduction induced by hypoxia and also inhibits ROS production. Indazole-Cl inhibits cell migration and invasion increased by hypoxia. It is a potent inhibitor of hypoxia-induced inflammation in vascular smooth muscle cells (VSMCs).
- Estrogen receptor (ER)-β-specific agonist
- Inflammatory effect
- Inhibits cyclooxygenase-2 expression reduction induced by hypoxia
- Inhibits ROS production
- Inhibits cell migration and invasion by hypoxia
- Potent inhibitor of hypoxia-induced inflammation in vascular smooth muscle cells (VSMCs)
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MEDCHEMEXPRESS LLC Abrucomstat (3-Nitroxypropanol) | 100502-66-7 | 95.0% | 121.09 | 50 MG
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Abrucomstat (3-Nitroxypropanol) is an orally active methyl coenzyme M reductase inhibitor that decreases ruminal methanogenesis. It is intended for research use only and is not sold to patients. The compound appears as a colorless to light yellow liquid with a density of 1.278±0.06 g/cm3.
- Functions as an orally active methyl coenzyme M reductase inhibitor
- Decreases ruminal methanogenesis
- Reduces methane emissions in calves based on in vivo studies
- Appears as a colorless to light yellow liquid
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MEDCHEMEXPRESS LLC 3-Indolyl acetate | 608-08-2 | 99.26% | 175.18 | 100 MG
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3-Indolyl acetate is an ester derivative of indole, found in various plant tissues, particularly in cruciferous vegetables. It acts as an important signaling molecule in plants, regulating physiological processes such as growth and defense against pathogens. It also shows potential in the pharmaceutical industry due to observed antitumor and anti-inflammatory effects in some studies. As a biochemical reagent, it can be used for life science research.
- Ester derivative of indole
- Found in various plant tissues
- Regulates physiological processes in plants
- Potential antitumor effects
- Potential anti-inflammatory effects
- Used as a biochemical reagent for life science research
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MEDCHEMEXPRESS LLC Indomethacin (Standard) | 53-86-1 | 99.6% | C₁₉H₁₆ClNO₄ | 250 MG
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Indomethacin (Standard) is the analytical standard for Indomethacin, intended for research and analytical applications. It is a potent, orally active COX1/2 inhibitor, with IC50 values of 18 nM for COX-1 and 26 nM for COX-2. It exhibits both anticancer and anti-infective activities.
- Analytical standard for Indomethacin.
- Potent, orally active COX1/2 inhibitor.
- IC50 values: 18 nM for COX-1 and 26 nM for COX-2.
- Possesses anticancer activity.
- Shows anti-infective activity.
- Used in research for cancer, inflammation, and viral infections.
- Suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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